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Some feel better within 2-3 weeks, others need several months

The area under the concentration curve obtained when administered at the same dose, corresponds approximately to twice that obtained when it is applied by oral or rectal route, as the active principle is metabolized almost 50% during its first passage through the liver (first pass effect), when administered by the routes mentioned

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So, your body cannot use your stored fats for energy

It can also increase your risk of falling

This timeline information helps set realistic expectations for users